A new family of high-affinity ABC manganese and zinc permeases.

  title={A new family of high-affinity ABC manganese and zinc permeases.},
  author={Jean-Pierre Claverys},
  journal={Research in microbiology},
  volume={152 3-4},
Phylogenetic analysis of 47 extracellular putative metal binding receptors (MBRs) belonging to the newly defined cluster suggests the existence of two subclusters. The question of substrate specificity of the corresponding ATP binding cassette (ABC) permeases is discussed, based on data collected from 19 of them concerning their regulation, metal requirement of permease mutants, metal uptake and metal binding. The proposal that the two subclusters correspond to paralogous metal permeases… CONTINUE READING

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