A new family of chimeric retrotranscripts formed by a full copy of U6 small nuclear RNA fused to the 3' terminus of l1.

@article{Buzdin2002ANF,
  title={A new family of chimeric retrotranscripts formed by a full copy of U6 small nuclear RNA fused to the 3' terminus of l1.},
  author={Anton Buzdin and Svetlana V. Ustyugova and Elena V Gogvadze and Tatiana Vinogradova and Yuri Lebedev and Eugene D. Sverdlov},
  journal={Genomics},
  year={2002},
  volume={80 4},
  pages={402-6}
}
Long interspersed nuclear elements (LINE-1, L1) constitute a large family of mammalian retrotransposons that have been replicating and evolving in mammals for more than 100 million years and now compose 17% of the human genome. They have an important creative role in human genomic evolution through mechanisms such as new integrations, generation of processed pseudogenes, and transfer of non-L1 DNA flanking their 3' ends to new genomic locations. Here we present evidence that the L1 integration… CONTINUE READING