A new experimental pancreatitis by incomplete closed duodenal loop: the influence of pancreatic microcirculation on the development and progression of induced severe pancreatitis in rats.


OBJECTIVES We developed a new model of reversible pancreatitis, as an incomplete closed duodenal loop (ICDL) model. This permitted us to demonstrate the process of progressing severity of pancreatitis and the influence of tissue microcirculation impairment on the morphologic changes of pancreatitis. METHODS An ICDL model was prepared in Wistar rats… (More)