A new era of semiconductor genetics using ion-sensitive field-effect transistors: the gene-sensitive integrated cell.

@article{Toumazou2014ANE,
  title={A new era of semiconductor genetics using ion-sensitive field-effect transistors: the gene-sensitive integrated cell.},
  author={Christofer Toumazou and Tan Sri Lim Kok Thay and Pantelis Georgiou},
  journal={Philosophical transactions. Series A, Mathematical, physical, and engineering sciences},
  year={2014},
  volume={372 2012},
  pages={20130112}
}
Semiconductor genetics is now disrupting the field of healthcare owing to the rapid parallelization and scaling of DNA sensing using ion-sensitive field-effect transistors (ISFETs) fabricated using commercial complementary metal -oxide semiconductor technology. The enabling concept of DNA reaction monitoring introduced by Toumazou has made this a reality and we are now seeing relentless scaling with Moore's law ultimately achieving the $100 genome. In this paper, we present the next evolution… CONTINUE READING
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