A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis.

Abstract

A new 4-(N,N-dimethylamino) phthalimide-based environment-sensitive fluorescent building block for solid phase peptide synthesis, has been synthesized and incorporated into peptides. Peptides incorporating this residue show great potential for biological applications in sensing protein/protein interactions. 

Topics

Cite this paper

@article{Vzquez2004ANE, title={A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis.}, author={M Eugenio V{\'a}zquez and Deborah M Rothman and Barbara Imperiali}, journal={Organic & biomolecular chemistry}, year={2004}, volume={2 14}, pages={1965-6} }