A new cytotoxic indole-3-ethenamide from the halotolerant fungus Aspergillus sclerotiorum PT06-1

@article{Wang2011ANC,
  title={A new cytotoxic indole-3-ethenamide from the halotolerant fungus Aspergillus sclerotiorum PT06-1},
  author={Hui Wang and Jin-Kai Zheng and Hai-jun Qu and Pei-Pei Liu and Yi Wang and Weiming Zhu},
  journal={The Journal of Antibiotics},
  year={2011},
  volume={64},
  pages={679-681}
}
A new cytotoxic indole-3-ethenamide (1) and two known compounds, 7-(3-methylbut-2-enyl)-1H-indole-3-carbaldehyde (2) and emodin (3) were isolated and identified from the ethyl acetate extract of Aspergillus sclerotiorum PT06-1 in a hypersaline nutrient-rich medium. On the basis of spectroscopic analysis and amino-acid analysis, the new structure of 1 was determined to be (S,E)-3-methyl-2-(N- methylacetamido)-N-(2-(7-(3-methylbut-2-enyl)-1H-indol-3-yl)vinyl)butanamide within 3:1 ratio of… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Cyclic tripeptides from the halotolerant fungus Aspergillus scler - otiorum PT 061

K. Liu, H. B. Wood, A. B. Jones
J . Nat . Prod . • 2010

CisTrans isomerization of organic molecules and biomolecules : implications and applications

S. G. Toske, P. R. Jensen, C. A. Kauffman, W. Fenical
Chem . Rev . • 2003

Total synthesis of asterriquinone B - 1

P. A. Cohen, G. H. N. Towers
Tetrahedron Lett . • 1999

Similar Papers

Loading similar papers…