A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum.

@article{Kong2010ANC,
  title={A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum.},
  author={Yue Kong and Jun-jun Xiao and Shu-cong Meng and Xiao-min Dong and Yue-Wei Ge and Ru-Feng Wang and Ming-Ying Shang and Shao-Qing Cai},
  journal={Fitoterapia},
  year={2010},
  volume={81 5},
  pages={367-70}
}
Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time. 

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