A new cytotoxic agent from solid-state fermented mycelium of Antrodia camphorata.

Abstract

Antroquinonol ( 1), an ubiquinone derivative, was isolated from the solid-state fermented mycelium of Antrodia camphorata (Polyporaceae, Aphyllophorales), a parasitic fungus indigenous to Taiwan. The structure of compound 1 was elucidated by the analysis of their spectroscopic data. Its cytotoxic activities were evaluated against MCF-7, MDA-MB-231 (human breast carcinoma), Hep3B, HepG2 (human liver carcinoma) and DU-145, LNCaP (human prostate carcinoma) cell lines, and the IC (50) values ranged from 0.13 +/- 0.02 to 6.09 +/- 0.07 microM.

Showing 1-10 of 13 extracted citations
05010020102011201220132014201520162017
Citations per Year

200 Citations

Semantic Scholar estimates that this publication has received between 34 and 637 citations based on the available data.

See our FAQ for additional information.