A new cytotoxic agent from solid-state fermented mycelium of Antrodia camphorata.

Abstract

Antroquinonol ( 1), an ubiquinone derivative, was isolated from the solid-state fermented mycelium of Antrodia camphorata (Polyporaceae, Aphyllophorales), a parasitic fungus indigenous to Taiwan. The structure of compound 1 was elucidated by the analysis of their spectroscopic data. Its cytotoxic activities were evaluated against MCF-7, MDA-MB-231 (human breast carcinoma), Hep3B, HepG2 (human liver carcinoma) and DU-145, LNCaP (human prostate carcinoma) cell lines, and the IC (50) values ranged from 0.13 +/- 0.02 to 6.09 +/- 0.07 microM.

050100200920102011201220132014201520162017
Citations per Year

162 Citations

Semantic Scholar estimates that this publication has 162 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Lee2007ANC, title={A new cytotoxic agent from solid-state fermented mycelium of Antrodia camphorata.}, author={Tzong-Huei Lee and Ching-Kuo Lee and Wan-Lin Tsou and Sheng-Yung Liu and Mao-Tien Kuo and Wu-Che Wen}, journal={Planta medica}, year={2007}, volume={73 13}, pages={1412-5} }