A new classification for HIV-1
@article{Berger1998ANC, title={A new classification for HIV-1}, author={E. Berger and R. Doms and E. Fenyö and B. Korber and D. Littman and J. Moore and Q. Sattentau and H. Schuitemaker and J. Sodroski and R. Weiss}, journal={Nature}, year={1998}, volume={391}, pages={240-240} }
The phenotype of HIV-1 isolates is defined by the cells in which they replicate in vitro, but these phenotypes can change in vivo with profound implications for viral transmission, pathogenesis and disease progression. Here we propose a new classification system based on co-receptor use, providing a more accurate description of viral phenotype than the present imprecise and often misleading classification schemes.
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References
SHOWING 1-4 OF 4 REFERENCES
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
- Biology, Medicine
- Cell
- 1996
- 3,076
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
- Biology, Medicine
- Nature
- 1996
- 2,852
Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry.
- Biology, Medicine
- Virology
- 1997
- 281