A new class of oxidosqualene cyclases directs synthesis of antimicrobial phytoprotectants in monocots.

@article{Haralampidis2001ANC,
  title={A new class of oxidosqualene cyclases directs synthesis of antimicrobial phytoprotectants in monocots.},
  author={Kosmas Haralampidis and Glenn J Bryan and Xiaoquan Qi and Kalliopi K Papadopoulou and Saleha Bakht and Rachel Melton and Anne Osbourn},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 23},
  pages={13431-6}
}
Many plants synthesize antimicrobial secondary metabolites as part of their normal program of growth and development, often sequestering them in tissues where they may protect against microbial attack. These include glycosylated triterpenoids (saponins), natural products that are exploited by man for a variety of purposes including use as drugs [Hostettmann, K. & Marston, A. (1995) Saponins (Cambridge Univ. Press, Cambridge, U.K.)]. Very little is known about the genes required for the… CONTINUE READING
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Saponins (Cambridge

  • K. Hostettmann, A. Marston
  • 1995

Molecular Cloning: A Laboratory Manual (Cold

  • J. Sambrook, E. F. Fritsch, T. Maniatis
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