A new class of drug for the management of type 2 diabetes: sodium glucose co-transporter inhibitors: 'glucuretics'.

@article{Chan2012ANC,
  title={A new class of drug for the management of type 2 diabetes: sodium glucose co-transporter inhibitors: 'glucuretics'.},
  author={H W Esther Chan and B Ashan and P S A Jayasekera and Andrew Collier and Sujoy Ghosh},
  journal={Diabetes & metabolic syndrome},
  year={2012},
  volume={6 4},
  pages={224-8}
}
BACKGROUND Type 2 diabetes is a common, chronic disease with a prevalence that is increasing at epidemic proportions. Management involves advice on lifestyle changes, oral anti-hyperglycaemic agents and/or insulin. The kidneys play a major role in the regulation of glucose, re-absorbing 99% of the plasma glucose filtered through the renal glomeruli tubules. The glucose transporter, SGLT2, which is found primarily in the S1 segment of the proximal renal tubule accounts for 90% of glucose re… CONTINUE READING