A new chemical tool for exploring the physiological function of the PDE2 isozyme.

@article{Chambers2006ANC,
  title={A new chemical tool for exploring the physiological function of the PDE2 isozyme.},
  author={Robert J. Chambers and Kristin Abrams and Norman Y. Garceau and Ajith V. Kamath and Christopher M Manley and Susan C Lilley and Douglas A. L. Otte and Dennis O. Scott and Alissa L Sheils and David A. Tess and A. Samuel Vellekoop and Yan Zhang and Kelvin T Lam},
  journal={Bioorganic & medicinal chemistry letters},
  year={2006},
  volume={16 2},
  pages={307-10}
}
Oxindole (2) is a potent and selective PDE2 inhibitor with a favorable ADME, physiochemical and pharmacokinetic profile to allow for use as a chemical tool in elucidating the physiological role of PDE2.