A new brain region for coordinating speech articulation

  title={A new brain region for coordinating speech articulation},
  author={Nina F. Dronkers},
HUMAN speech requires complex planning and coordination of mouth and tongue movements. Certain types of brain injury can lead to a condition known as apraxia of speech, in which patients are impaired in their ability to coordinate speech movements but their ability to perceive speech sounds, including their own errors, is unaffected1,3. The brain regions involved in coordinating speech, however, remain largely unknown. In this study, brain lesions of 25 stroke patients with a disorder in the… 

The Precentral Insular Cortical Network for Speech Articulation.

The present study demonstrates the critical circuit for the coordination of complex articulatory movements prior to and during the execution of the motor speech plans, different from those that relate to the cognitive aspects of language production.

Re-examining the brain regions crucial for orchestrating speech articulation.

In patients with and without insular lesions, apraxia of speech was associated with structural damage or low blood flow in left posterior inferior frontal gyrus, and this results illustrate a potential limitation of lesion overlap studies, and illustrate an alternative method for identifying brain-behaviour relationships.

Motor planning center for speech articulation in the normal human brain.

Results suggest that the deep frontal region is involved in the articulatory programming of speech movements in the dominant hemisphere of the normal human brain.

Speech motor programming in apraxia of speech

Patients with AOS have a specific deficit in assembling motor plans for alternating syllable utterances, which is considered relevant in the understanding of the normal processes of spoken language production.

Pure Apraxia of Speech After Resection Based in the Posterior Middle Frontal Gyrus.

While not a classical language area, emerging literature supports the role of this area in the production of fluent speech, and has implications for surgical planning and the general neurobiology of language.

Uncovering the functional anatomy of the human insula during speech

The conclusion that the insula does not serve pre-articulatory preparatory roles is supported by a series of experiments on single-word articulations of varying complexity, non-speech orofacial movements and speech listening in a cohort of 27 patients implanted with penetrating intracranial electrodes.

Activation of right insular cortex during imaginary speech articulation

The current magnetoencephalography study, in which 12 participants were required to imagine vocalizing a phonogram after a visual cue, was designed to visualize the prearticulatory ‘automatic’ processes corresponding to the motor initiation, suggesting that motor control of speech proceeds from the insular regions.

Functional Characterization of the Human Speech Articulation Network

A number of brain regions have been implicated in articulation, but their precise computations remain debated. Using functional magnetic resonance imaging, we examine the degree of functional



Language localization and variability

Higher Cortical Functions in Man

Among the authors' patients was a bookkeeper with a severe form of sensory aphasia who could still draw up the annual balance sheet in spite of severe disturbances of speech and although he was unable to remember the names of his subordinates and used to refer to them incorrectly.

Phonemic variability in apraxia of speech.

Articulatory performance in the condition apraxia of speech was analyzed in 10 patients and compared with the performance of 10 dysarthric and 10 normal subjects.

Differential language and neurologic characteristics in cerebral involvement.

Four groups of 10 patients, each group having a different neurogenic disorder of communication, were tested for impairment in 10 language categories, and the most strongly differentiating disabilities in the four groups were aphasia, apraxia of speech, confused language, and general intellectual impairment.

The neural correlates of the verbal component of working memory

Comparisons of distribution of cerebral blood flow in these conditions localized the phonological store to the left supramarginal gyrus whereas the subvocal rehearsal system was associated with Broca's area, the first demonstration of the normal anatomy of the components of the 'articulatory loop'.

The insular lobe in primates including humans.

The broad concept of the insula has been outlined and it is demonstrated that the insular lobe has connections with portions of the frontal, parietal, and temporal lobes as well as of the cingulate gyrus.

Aphemia. Clinical-anatomic correlations.

Clinical and anatomic data is gathered on four patients with this dysarthria without aphasia, caused by small lesions of the motor system for articulation: pars opercularis, inferior prerolandic gyrus, or white matter deep to those regions.