A new blood-flow pharmacokinetic model for ethanol

  title={A new blood-flow pharmacokinetic model for ethanol},
  author={Jay L. Rheingold and Richard E. Lindstrom and Dr. Paul K. Wilkinson},
  journal={Journal of Pharmacokinetics and Biopharmaceutics},
A multicompartmental mathematical model, taking into account observed vascular concentration gradients and blood flow rate limitations, has been proposed. Based on blood flows and blood and tissue volumes reported in the literature and in personal communications, an appropriate model was elaborated for ethanol in the dog. The relatively high values of r2… CONTINUE READING