A new bisabolane-type sesquiterpenoid from the fermentation broth of fungus Antrodiella gypsea

@article{Zhao2016ANB,
  title={A new bisabolane-type sesquiterpenoid from the fermentation broth of fungus Antrodiella gypsea},
  author={Zhen-Zhu Zhao and Li-Qiang He and Heping Chen and Zheng-Hui Li and Zejun Dong and Tao Feng and Ji-Kai Liu},
  journal={Journal of Asian Natural Products Research},
  year={2016},
  volume={18},
  pages={184 - 188}
}
Studies of the fermentation broth of fungus Antrodiella gypsea led to the isolation of a new bisabolane-type sesquiterpenoid that was named gypseatriol (1), together with the known compound 2,10-dodecadiene-1,6,7-triol (2). The structure of this new metabolite was assigned by analysis of 2D NMR and HR-EI-MS. Absolute configuration was assigned by single crystal X-ray diffraction analysis. Compound 1 was evaluated for its antifungal activity on Candida albicans. 
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References

SHOWING 1-10 OF 13 REFERENCES
Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea
Three new humulane-type sesquiterpenes, antrodols A–C (1–3), were isolated from cultures of the fungus Antrodiella albocinnamomea. Their structures were elucidated on the basis of extensive…
Three novel degraded steroids from cultures of the Basidiomycete Antrodiella albocinnamomea
TLDR
Three novel degraded steroids, named albocisterols A-C (1-3), have been isolated from cultures of Antrodiella al bocinnamomea and exhibited significant inhibitory activities against protein tyrosine phosphatase 1B (PTP1B).
Biocatalyzed cross-coupling of sinomenine and guaiacol by Antrodiella semisupina.
TLDR
Biocatalyzed cross-coupling of sinomenine and guaiacol by Antrodiella semisupina provided two unique C-C coupled and one C-O linked novel metabolites, which exhibited more potent inhibitory activity on IL-6 production than 1 in human synovial sarcoma cell (SW982) and stimulated IL- 6 production.
Enantioselective synthesis of (3R,6S,7R,18R,19S)-, (3R,6S,7R,18R,19R)-, and (3R,6S,7R,18S,19R)-Quassiols A. A comment on the stereochemistry of natural quassiol A
Abstract (3R,6S,7R,18R,19S)-, (3R,6S,7R,18R,19R)-, and (3R,6S,7R,18S,19R)-Quassiols A were synthesized enantioselectively by using baker's yeast reduction and asymmetric dihydroxylation, but their…
Nat
  • Prod. Bioprospect. 4, 207
  • 2014
Steroids 87
  • 21
  • 2014
Chinese Patent No
  • CN103122315A
  • 2013
Sci
  • Technol. 21, 8
  • 2013
Mycosystema 31
  • 486
  • 2012
Mycosystema 28
  • 315
  • 2009
...
1
2
...