A new bisabolane-type sesquiterpenoid from the fermentation broth of fungus Antrodiella gypsea

  title={A new bisabolane-type sesquiterpenoid from the fermentation broth of fungus Antrodiella gypsea},
  author={Zhen-Zhu Zhao and Li He and Heping Chen and Zheng-Hui Li and Zejun Dong and Tao Feng and Jikai Liu},
  journal={Journal of Asian Natural Products Research},
  pages={184 - 188}
Studies of the fermentation broth of fungus Antrodiella gypsea led to the isolation of a new bisabolane-type sesquiterpenoid that was named gypseatriol (1), together with the known compound 2,10-dodecadiene-1,6,7-triol (2). The structure of this new metabolite was assigned by analysis of 2D NMR and HR-EI-MS. Absolute configuration was assigned by single crystal X-ray diffraction analysis. Compound 1 was evaluated for its antifungal activity on Candida albicans. 
6 Citations

Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans.

Remarkably, curtachalasin C (1) showed significant resistance reversal activity against fluconazole-resistant Candida albicans.

Bisabolane-type sesquiterpenoids with potential anti-inflammatory and anti-HIV activities from the stems and leaves of Morinda citrifolia.

A new naturally occurring bisabolane-type sesquiterpenoid, morincitrinoid A, together with five known analogues (2-6) was isolated from Morinda citrifolia for the first time and the chemical structure of 1 was elucidated by comprehensive spectral analyses.

Secondary Metabolites from Higher Fungi.

This chapter gives a comprehensive overview of the secondary metabolites from higher fungi, with 765 references highlighting the isolation, structure elucidation, biological activities, chemical syntheses, and biosynthesis of pigments, nitrogen-containing compounds, and terpenoids from mushrooms.

Survey of natural products reported by Asian research groups in 2016

The advances that Asian research groups made in the field of natural products chemistry in 2016 were summarized and compounds with unique structural features and/or promising bioactivities originating from Asian natural sources were discussed based on structural classification.



Biocatalyzed cross-coupling of sinomenine and guaiacol by Antrodiella semisupina.

Biocatalyzed cross-coupling of sinomenine and guaiacol by Antrodiella semisupina provided two unique C-C coupled and one C-O linked novel metabolites, which exhibited more potent inhibitory activity on IL-6 production than 1 in human synovial sarcoma cell (SW982) and stimulated IL- 6 production.

Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea

Three new humulane-type sesquiterpenes, antrodols A–C (1–3), were isolated from cultures of the fungus Antrodiella albocinnamomea. Their structures were elucidated on the basis of extensive


  • Technol. 21, 8
  • 2013

Mycosystema 31

  • 486
  • 2012

Steroids 87

  • 21
  • 2014


  • Lett. 10, 1119
  • 2008

Chinese Patent No

  • CN103122315A
  • 2013

Mycosystema 28

  • 315
  • 2009