A new biomarker of hedonic eating? A preliminary investigation of cortisol and nausea responses to acute opioid blockade.

@article{Daubenmier2014ANB,
  title={A new biomarker of hedonic eating? A preliminary investigation of cortisol and nausea responses to acute opioid blockade.},
  author={Jennifer J Daubenmier and Robert H. Lustig and Frederick M. Hecht and J. Kristeller and Joshua D Woolley and Tanja C M Adam and Mary F. Dallman and Elissa E Epel},
  journal={Appetite},
  year={2014},
  volume={74},
  pages={92-100}
}
Overweight and obese individuals differ in their degree of hedonic eating. This may reflect adaptations in reward-related neural circuits, regulated in part by opioidergic activity. We examined an indirect, functional measure of central opioidergic activity by assessing cortisol and nausea responses to acute opioid blockade using the opioid antagonist naltrexone in overweight/obese women (mean BMI=31.1±4.8) prior to the start of a mindfulness-based intervention to reduce stress eating. In… CONTINUE READING

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