A new bioactive aminophenoxazinone alkaloid from a marine-derived actinomycete

  title={A new bioactive aminophenoxazinone alkaloid from a marine-derived actinomycete},
  author={Mohamed Saleh Abdelfattah},
  journal={Natural Product Research},
  pages={2126 - 2131}
  • M. Abdelfattah
  • Published 1 November 2013
  • Chemistry, Biology
  • Natural Product Research
Chemical investigation of the marine Streptomyces sp. Eg25 led to the isolation of one new natural 2-aminophenoxazin-3-one-8-carboxylic acid methyl ester named maroxazinone (1) as well as the known compounds elloxazinone A (2), exfoliazone (3), carboxyexfoliazone (4), elloxazinone B (5) and venezueline D (6). The chemical structures of the isolated compounds were deduced from extensive studies of NMR (1H and 13C NMR, 1H–1H COSY, HMQC and HMBC) and mass spectra. The cytotoxic activities of the… 

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