A new assay for CCR5del32 mutation: genotyping through the number of fragments amplified.

Abstract

CCR5 is a coreceptor for the entry of HIV into CD4+ cells and some of its natural mutants possess potential protection against HIV-1 infection. Individuals with the CCR5-delta32 genotype have a lower possibility of being infected with HIV and take longer to progress to AIDS if infected. The present study demonstrated a new primer extension assay for genetic… (More)

Topics

Cite this paper

@article{Wang2011ANA, title={A new assay for CCR5del32 mutation: genotyping through the number of fragments amplified.}, author={Qinglin Wang and Li Xiao and Jia Zhang and Nongyue He and Xue-guan Lu and Ping Li and Kai Li}, journal={Journal of biomedical nanotechnology}, year={2011}, volume={7 6}, pages={754-8} }