A new approach to screening cancer stem cells from the U251 human glioma cell line based on cell growth state.

@article{Cao2013ANA,
  title={A new approach to screening cancer stem cells from the U251 human glioma cell line based on cell growth state.},
  author={Xiangmei Cao and Yu Gu and Lina Jiang and Yingmei Wang and Fang ai Liu and Yuqiao Xu and Junxia Deng and Yayun Nan and Liying Zhang and Jing Ye and Qing Li},
  journal={Oncology reports},
  year={2013},
  volume={29 3},
  pages={1013-8}
}
Cancer stem cells (CSCs) play important roles in the biological behaviour of malignant tumours. To study their properties, they must be carefully identified and purified. Cancer cells can acquire three different morphological types during single cell cloning. A small subpopulation of clones acquires a regular and compact shape, and these clones are enriched for CSCs; however, the majority of clones have an irregular morphology with… CONTINUE READING
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