A new approach to cancer therapy due to appropriate uptake and retention kinetics of meta-tetrahydroxy-phenylchlorin in a human fibroblast cell line.

@article{Wierrani1996ANA,
  title={A new approach to cancer therapy due to appropriate uptake and retention kinetics of meta-tetrahydroxy-phenylchlorin in a human fibroblast cell line.},
  author={Franz Wierrani and Dorothea Fiedler and G M Schnitzhofer and James C. Stewart and Kamran Gharehbaghi and Mireille Henry and Wolfgang Grin and Werner Gr{\"u}nberger and Barbara Krammer},
  journal={Cancer biochemistry biophysics},
  year={1996},
  volume={15 3},
  pages={171-6}
}
Studies have shown that meta-tetrahydroxy-phenylchlorin is an efficient tumor targeting agent for laser photodynamic therapy. The effectiveness of this approach for cancer treatment depends on drug concentration, incubation time and extracellular protein. We studied uptake and retention kinetics of mTHPC in a human fibroblast cell line. Our results clearly… CONTINUE READING