A new approach for the development of tracers: data base screening and in silico modeling for the identification of new ligands for SSTR2.

@article{Cheng2008ANA,
  title={A new approach for the development of tracers: data base screening and in silico modeling for the identification of new ligands for SSTR2.},
  author={Caixia Cheng and Leyun Pan and Antonia Dimitrakopoulou-Strauss and Ludwig G. Strauss},
  journal={Hellenic journal of nuclear medicine},
  year={2008},
  volume={11 2},
  pages={101-4}
}
New ligands are needed to improve diagnostics and treatment of SSTR2 expressing tumors. We implemented a procedure to identify ligands based on computer processing methods. A multistep procedure was used. Search entries were taken from National Cancer Institute database. Application of criteria defined by the Lipinski rules reduced the initial data set… CONTINUE READING