A new approach for the development of tracers: data base screening and in silico modeling for the identification of new ligands for SSTR2.

Abstract

New ligands are needed to improve diagnostics and treatment of SSTR2 expressing tumors. We implemented a procedure to identify ligands based on computer processing methods. A multistep procedure was used. Search entries were taken from National Cancer Institute database. Application of criteria defined by the Lipinski rules reduced the initial data set… (More)

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@article{Cheng2008ANA, title={A new approach for the development of tracers: data base screening and in silico modeling for the identification of new ligands for SSTR2.}, author={Caixia Cheng and Leyun Pan and Antonia Dimitrakopoulou-Strauss and Ludwig G. Strauss}, journal={Hellenic journal of nuclear medicine}, year={2008}, volume={11 2}, pages={101-4} }