A new approach for efficient genotype imputation using information from relatives

@inproceedings{Sargolzaei2013ANA,
  title={A new approach for efficient genotype imputation using information from relatives},
  author={Mehdi Sargolzaei and Jacques P Chesnais and Flavio S. Schenkel},
  booktitle={BMC Genomics},
  year={2013}
}
Genotype imputation can help reduce genotyping costs particularly for implementation of genomic selection. In applications entailing large populations, recovering the genotypes of untyped loci using information from reference individuals that were genotyped with a higher density panel is computationally challenging. Popular imputation methods are based upon the Hidden Markov model and have computational constraints due to an intensive sampling process. A fast, deterministic approach, which… CONTINUE READING
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