A new antitumor antibiotic, awamycin.

@article{Umezawa1983ANA,
  title={A new antitumor antibiotic, awamycin.},
  author={I. Umezawa and H. Oka and K. Komiyama and K. Hagiwara and S. Tomisaka and T. Miyano},
  journal={The Journal of antibiotics},
  year={1983},
  volume={36 9},
  pages={
          1144-9
        }
}
A new antibiotic, awamycin, was isolated from the culture broth of Streptomyces sp. No. 80-217. It appeared to belong to the quinone indicator group from results of physicochemical studies and has the empirical formula C38H49NO12S. This antibiotic possessed antibacterial and antitumor activities against Gram-positive bacteria and experimental murine tumors. The antibiotic also showed direct cytotoxic activity against HeLa cells in vitro. 
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