A new angiographic method to assess coronary flow reserve-validation in humans.

@article{Rittger2010ANA,
  title={A new angiographic method to assess coronary flow reserve-validation in humans.},
  author={Harald Rittger and Asher Kuper and O Breithardt and Eberhardt Kuon and Martin Schmidt and Anil-Martin Sinha and Barbara J F Bl{\"u}m and Axel R. Jakob and Johannes Brachmann},
  journal={Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions},
  year={2010},
  volume={75 2},
  pages={
          167-73
        }
}
BACKGROUND Coronary flow reserve (CFR) is defined as the ratio between coronary artery flow during maximal hyperemia and rest. It is considered as a marker for the integrity of the epicardial coronary circulation and the microcirculation. CFR measurement typically requires the introduction of a guide wire into a diseased coronary artery. We tested a new algorithm, which allows to estimate CFR by analysis of coronary angiograms without the need for direct intracoronary measurements. METHODS… CONTINUE READING
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