A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors.

Abstract

The signaling molecule nitric oxide (NO) could engage multiple pathways to influence cellular function. Unraveling their relative biological importance has been difficult because it has not been possible to administer NO under the steady-state conditions that are normally axiomatic for analyzing ligand-receptor interactions and downstream signal… (More)

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@article{Griffiths2003ANA, title={A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors.}, author={Charmaine H Griffiths and Victoria Wykes and Tomas C. Bellamy and John Garthwaite}, journal={Molecular pharmacology}, year={2003}, volume={64 6}, pages={1349-56} }