A new allele of ocular retardation: Early development and morphogenetic cell death

  title={A new allele of ocular retardation: Early development and morphogenetic cell death},
  author={Karl Theiler and Don S. Varnum and Joseph H. Nadeau and Leroy C. Stevens and Bernhard Cagianut},
  journal={Anatomy and Embryology},
The inheritance and some developmental effects of a new allele of ocular retardation (or J) are described. Affected animals, at 12 days of gestation, show reduced cell death in the eye cup and thickening of the inner wall of the optic fissure. At 11 to 13 days of gestation or 3/or J eyes grafted to the testis do not produce retina as their or J+ littermates do. Adult animals have small eyes with closed lids, abnormal retinal layers, and no optic nerve. 


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