Corpus ID: 46091610

A new active steroidal saponin from Anemarrhena asphodeloides.

  title={A new active steroidal saponin from Anemarrhena asphodeloides.},
  author={J. X. Dong and G. Han},
  journal={Planta medica},
  volume={57 5},
  • J. X. Dong, G. Han
  • Published 1991
  • Medicine
  • Planta medica
  • A new active steroidal saponin, anemarsaponin B, was isolated from the rhizomes of Anemarrhina asphodeloides. The structure of anemarsaponin B was elucidated as 26-O-beta-D-glucopyranosylfurost-20(22)-ene-3 beta, 26-diol-3-O-beta-D-glucopyranosyl-(1----2)-beta-D-galactopyranoside by chemical and spectral studies. Preliminary pharmacological tests showed that anemarsaponin B could inhibit PAF-induced rabbit platelet aggregation in vitro. 
    11 Citations
    Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways.
    • Jiyeon Kim, J. Shin, +4 authors Kyung-Tae Lee
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    Anticolitic Effect of the Rhizome Mixture of Anemarrhena asphodeloides and Coptidis chinensis (AC-mix) in Mice
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    A Review of Antiplatelet Activity of Traditional Medicinal Herbs on Integrative Medicine Studies
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