A new RNA polymerase sigma factor, sigma F, is required for the late stages of morphological differentiation in Streptomyces spp.

@article{Potkov1995ANR,
  title={A new RNA polymerase sigma factor, sigma F, is required for the late stages of morphological differentiation in Streptomyces spp.},
  author={L. Pot{\'u}{\vc}kov{\'a} and Gabriella H. Kelemen and Kim C. Findlay and Michael A Lonetto and Mark J. Buttner and Jan Kormanec},
  journal={Molecular microbiology},
  year={1995},
  volume={17 1},
  pages={37-48}
}
A gene (sigF) encoding a new sigma factor was isolated from Streptomyces aureofaciens using a degenerate oligonucleotide probe designed from the GLI(KDNE)A motif lying within the well-conserved region 2.2 of the eubacterial sigma 70 family. Homologues were present in other Streptomyces spp., and that of the genetically well studied Streptomyces coelicolor A3(2) was also cloned. The nucleotide sequences of the two sigF genes were determined and shown to encode primary translation products of 287… CONTINUE READING

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