A new DNA nanostructure, the G-wire, imaged by scanning probe microscopy.

  title={A new DNA nanostructure, the G-wire, imaged by scanning probe microscopy.},
  author={Tom C Marsh and James Vesenka and Eric Henderson},
  journal={Nucleic acids research},
  volume={23 4},
G-DNA is a polymorphic family of quadruple helical nucleic acid structures containing guanine tetrad motifs [G-quartets; Williamson, J.R., Raghuraman, M.K. and Cech, T.R. (1989) Cell 59, 871-880; Williamson, J.R. (1993) Proc. Natl. Acad. Sci. USA 90, 3124-3124]. Guanine rich oligonucleotides that are self-complimentary, as found in many telomeric G-strand repeat sequences, form G-DNA in the presence of monovalent and/or divalent metal cations. In this report we use the atomic force microscope… CONTINUE READING
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