A neutral glycoprotease of Pasteurella haemolytica A1 specifically cleaves O-sialoglycoproteins.

@article{Abdullah1992ANG,
  title={A neutral glycoprotease of Pasteurella haemolytica A1 specifically cleaves O-sialoglycoproteins.},
  author={Kamaruddin Abdullah and E. Udoh and Patricia Elisabeth Shewen and A. E. Mellors},
  journal={Infection and immunity},
  year={1992},
  volume={60 1},
  pages={56-62}
}
A neutral metalloprotease with marked specificity for an O-sialoglycoprotein has been isolated from culture supernatants of Pasteurella haemolytica A1. The 35-kDa enzyme cleaves human erythrocyte glycophorin A, which is O glycosylated, but does not cleave N-glycosylated proteins or nonglycosylated proteins. Glycophorin A was cleaved when it was present in… CONTINUE READING