A neuropeptide Y locus on chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat.

@article{Katsuya1993ANY,
  title={A neuropeptide Y locus on chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat.},
  author={Tomohiro Katsuya and Jitsuo Higaki and Yan Zhao and Tetsuro Miki and Hiroshi Mikami and Tadao Serikawa and Toshio Ogihara},
  journal={Biochemical and biophysical research communications},
  year={1993},
  volume={192 1},
  pages={261-7}
}
Recent advances in molecular biology have allowed the study of the candidate genes for essential hypertension. To identify the genes responsible for basal blood pressure in the spontaneously hypertensive rat strain, the rat model of genetic hypertension, we performed a cosegregation analysis between the genotype and blood pressure in a set of male F2 progeny obtained from SHR and Wistar-Kyoto rats, a reference normotensive strain. Our investigation revealed that a locus on the chromosome 4… CONTINUE READING

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Genetic analysis of inherited hypertension in the rat.

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Increased blood pressure responses in neuropeptide Y transgenic rats.

American journal of physiology. Regulatory, integrative and comparative physiology • 2001
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Gap junction protein locus on chromosome 18 cosegregates with body weight in the spontaneously hypertensive rat.

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