A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome

@article{Morris2012ANM,
  title={A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome},
  author={Gerwyn Morris and Michael Maes},
  journal={Metabolic Brain Disease},
  year={2012},
  volume={28},
  pages={523-540}
}
This paper proposes a neuro-immune model for Myalgic Encephalomyelitis/Chronic fatigue syndrome (ME/CFS). A wide range of immunological and neurological abnormalities have been reported in people suffering from ME/CFS. They include abnormalities in proinflammatory cytokines, raised production of nuclear factor-κB, mitochondrial dysfunctions, autoimmune responses, autonomic disturbances and brain pathology. Raised levels of oxidative and nitrosative stress (O&NS), together with reduced levels of… CONTINUE READING