A neurally enriched coronin-like protein, ClipinC, is a novel candidate for an actin cytoskeleton-cortical membrane-linking protein.

@article{Nakamura1999ANE,
  title={A neurally enriched coronin-like protein, ClipinC, is a novel candidate for an actin cytoskeleton-cortical membrane-linking protein.},
  author={Tsutomu Nakamura and Kosei Takeuchi and Shizuko Muraoka and Hideo Takezoe and Noriko Takahashi and Nozomu Mori},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 19},
  pages={13322-7}
}
Brain-enriched human FC96 protein shows a close sequence similarity to the Dictyostelium actin-binding protein coronin, which has been implicated in cell motility, cytokinesis, and phagocytosis. A phylogenetic tree analysis revealed that FC96 and two other mammalian molecules (p57 and IR10) form a new protein family, the coronin-like protein (Clipin) family; thus hereafter we refer to FC96 as ClipinC. A WD domain and a succeeding alpha-helical region are conserved among coronin and Clipin… CONTINUE READING

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