A networks method for ranking microRNA dysregulation in cancer

@article{Budd2013ANM,
  title={A networks method for ranking microRNA dysregulation in cancer},
  author={W. Budd and Sarah Seashols and Danielle Weaver and Cyriac Joseph and Z. Zehner},
  journal={BMC Systems Biology},
  year={2013},
  volume={7},
  pages={S3 - S3}
}
BackgroundDespite the lack of agreement on their exact roles, it is known that miRNAs contribute to cancer progression. Many studies utilize methods to detect differential regulation of miRNA expression. It is prohibitively expensive to examine all potentially dysregulated miRNAs and traditionally, researchers have focused their efforts on the most extremely dysregulated miRNAs. These methods may overlook the contribution of less differentially expressed but more functionally relevant miRNAs… Expand

References

SHOWING 1-10 OF 56 REFERENCES
microRNA Dysregulation in Prostate Cancer: Network Analysis Reveals Preferential Regulation of Highly Connected Nodes
The transcriptional regulation of miR-21, its multiple transcripts and their implication in prostate cancer
miRecords: an integrated resource for microRNA–target interactions
miR-21: an oncomir on strike in prostate cancer
Oncomirs — microRNAs with a role in cancer
miR2Disease: a manually curated database for microRNA deregulation in human disease
The database of experimentally supported targets: a functional update of TarBase
Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells
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