A network perspective on the virus world

  title={A network perspective on the virus world},
  author={Jaime Iranzo and Mart Krupovic and Eugene V. Koonin},
  journal={Communicative \& Integrative Biology},
  pages={e00978 - 16}
ABSTRACT Viral evolution is characterized by high rates of horizontal gene transfer and fast sequence divergence. Furthermore, there are no universal genes shared by all viruses. As a result, distant relationships among viruses are better represented by a network than by a tree. Here we discuss 3 network representations of the virus world with decreasing levels of complexity, from a multilayer network that integrates sequence conservation and patterns of gene sharing to a classic genome… 
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