A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer

@inproceedings{Yeh2011ANF,
  title={A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer},
  author={Shih-Heng Yeh and Hsiang-Yuan Yeh and Von-Wun Soo},
  booktitle={Journal of Clinical Bioinformatics},
  year={2011}
}
Systematic approach for drug discovery is an emerging discipline in systems biology research area. It aims at integrating interaction data and experimental data to elucidate diseases and also raises new issues in drug discovery for cancer treatment. However, drug target discovery is still at a trial-and-error experimental stage and it is a challenging task to develop a prediction model that can systematically detect possible drug targets to deal with complex diseases. We integrate gene… CONTINUE READING