A network-based gene-weighting approach for pathway analysis

@article{Fang2012ANG,
  title={A network-based gene-weighting approach for pathway analysis},
  author={Zhaoyuan Fang and Weidong Tian and Hongbin Ji},
  journal={Cell Research},
  year={2012},
  volume={22},
  pages={565-580}
}
Classical algorithms aiming at identifying biological pathways significantly related to studying conditions frequently reduced pathways to gene sets, with an obvious ignorance of the constitutive non-equivalence of various genes within a defined pathway. We here designed a network-based method to determine such non-equivalence in terms of gene weights. The gene weights determined are biologically consistent and robust to network perturbations. By integrating the gene weights into the classical… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 58 REFERENCES

Similar Papers

Loading similar papers…