A network-based approach to quantifying the impact of biologically active substances.

@article{Hoeng2012ANA,
  title={A network-based approach to quantifying the impact of biologically active substances.},
  author={Julia Hoeng and Renee Deehan and Dexter Pratt and Florian Georg Martin and Alain Sewer and Ty M. Thomson and David A. Drubin and Christina A Waters and David de Graaf and Manuel C. Peitsch},
  journal={Drug discovery today},
  year={2012},
  volume={17 9-10},
  pages={
          413-8
        }
}
Fe at u re s P E R S P E C T IV E Society increasingly demands close scrutiny of the potential health risks of long-term exposure to biologically active substances, such as therapeutic drugs or environmental toxins. Such risks are typically assessed a posteriori through clinical epidemiology studies. However, disease might take decades to manifest, at a point where changes in therapeutic regime, life style or exposure would not prevent disease onset. Moreover, disease risk as assessed… CONTINUE READING
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