A negative direct antiglobulin test with strong IgG red cell autoantibodies present in the serum of a patient with autoimmune haemolytic anaemia.

@article{Veer1981AND,
  title={A negative direct antiglobulin test with strong IgG red cell autoantibodies present in the serum of a patient with autoimmune haemolytic anaemia.},
  author={Mars B van't Veer and P M van Wieringen and Inge van Leeuwen and Marijke A M Overbeeke and Albert E G K R von dem Borne and C. P. Engelfriet},
  journal={British journal of haematology},
  year={1981},
  volume={49 3},
  pages={383-6}
}
The case is presented of a boy with an autoimmune haemolytic anaemia of 10 years duration. He had a positive direct antiglobulin test with IgG and complement detected on the red cells and with IgG autoantibodies in the serum. During a recent episode of severe haemolysis, the Hb level fell to 3.8 g/dl and the direct antiglobulin test became negative although his autoantibodies still reacted with all the red cells in a panel. The serum reacted more strongly with C- and e-positive cells. The Rh… CONTINUE READING