A near fatal case of the dapsone hypersensitivity syndrome in a patient with urticarial vasculitis.

@article{Leslie2003ANF,
  title={A near fatal case of the dapsone hypersensitivity syndrome in a patient with urticarial vasculitis.},
  author={Kieron S. Leslie and Kristin L Gaffney and Calum N. Ross and Saxon Ridley and Tim H Barker and Jennifer J. Garioch},
  journal={Clinical and experimental dermatology},
  year={2003},
  volume={28 5},
  pages={496-8}
}
Dapsone (4,4'-diaminodiphenyl sulphone) is used for a variety of dermatological conditions including immunobullous diseases and urticarial vasculitis. Side-effects are common and include lethargy, headaches, methaemoglobinaemia and haemolysis. Severe adverse effects are rare but the dapsone hypersensitivity syndrome is well recognized. Symptoms include fever, haemolytic anaemia, lymphocytosis and hepatitis. We report a near fatal case of the dapsone hypersensitivity syndrome in a patient with… CONTINUE READING
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