A naturally occurring structural variant of human growth hormone.

@article{Lewis1978ANO,
  title={A naturally occurring structural variant of human growth hormone.},
  author={U. J. Lewis and J T Dunn and Lynda F. Bonewald and B K Seavey and W P Vanderlaan},
  journal={The Journal of biological chemistry},
  year={1978},
  volume={253 8},
  pages={2679-87}
}
A structural variant of human growth hormone was isolated from pituitary extracts. The newly recognized modification had a molecular weight of 20,000 when analyzed by electrophoresis in sodium dodecyl sulfate, whereas human growth hormone gave a value near 22,000. By isoelectric focusing the variant had a p1 of 5.85; human growth hormone had a value of 5.6. All extracts of 30 individual fresh frozen pituitary glands, analyzed by electrophoresis in sodium dodecyl sulfate, contained the 20,000… CONTINUE READING