A national validation project of alternative methods to the Draize rabbit eye test.

@article{Kalweit1990ANV,
  title={A national validation project of alternative methods to the Draize rabbit eye test.},
  author={S Kalweit and R Besoke and Ingrid Gerner and H. Spielmann},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={1990},
  volume={4 4-5},
  pages={
          702-6
        }
}
In June 1988, a 2.5-yr inter-laboratory study involving 13 toxicology laboratories was started in West Germany to validate alternative methods to the Draize rabbit eye test. The aim of this collaborative study is to validate the classification of chemicals with regard to their irritation potential using the neutral red/kenacid blue (NR/KB) cytotoxicity assay and the hen's egg test-chorioallantoic membrane (HET-CAM) assay. The results should make it possible to decide whether and to what extent… CONTINUE READING

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