A nanoporous reactor for efficient proteolysis.

@article{Qiao2008ANR,
  title={A nanoporous reactor for efficient proteolysis.},
  author={Liang Qiao and Yun Liu and Sarah P. Hudson and Pengyuan Y. Yang and Edmond Magner and Baohong Liu},
  journal={Chemistry},
  year={2008},
  volume={14 1},
  pages={
          151-7
        }
}
A nanoreactor based on mesoporous silicates is described for efficient tryptic digestion of proteins within the mesochannels. Cyano-functionalized mesoporous silicate (CNS), with an average pore diameter of 18 nm, is a good support for trypsin, with rapid in situ digestion of the model proteins, cytochrome c and myoglobin. The generated peptides were analyzed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Proteolysis by trypsin-CNS is much more… CONTINUE READING
Highly Cited
This paper has 25 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Study on an integrated process combining ozonation with ceramic ultra-filtration for decentralized supply of drinking water.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering • 2014
View 1 Excerpt