A nanoparticle label/immunochromatographic electrochemical biosensor for rapid and sensitive detection of prostate-specific antigen.

@article{Lin2008ANL,
  title={A nanoparticle label/immunochromatographic electrochemical biosensor for rapid and sensitive detection of prostate-specific antigen.},
  author={Y. Lin and Jun Tao Wang and Guodong Liu and Hong D Isaac Wu and Chien M. Wai and Yuehe Lin},
  journal={Biosensors & bioelectronics},
  year={2008},
  volume={23 11},
  pages={
          1659-65
        }
}
We present a nanoparticle (NP) label/immunochromatographic electrochemical biosensor (IEB) for rapid and sensitive detection of prostate-specific antigen (PSA) in human serum. This IEB integrates the immunochromatographic strip with the electrochemical detector for transducing quantitative signals. The NP label, made of CdSe@ZnS, serves as a signal-amplifier vehicle. A sandwich immunoreaction was performed on the immunochromatographic strip. The captured NP labels in the test zone were… CONTINUE READING
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