A nanofibrous sheet-based system for linear delivery of nifedipine.

Abstract

We developed a nanofibrous sheet-based system to achieve linear release of nifedipine for oral delivery. The nanofibrous sheets of micro-porosity were fabricated by the electrospinning method, using a biocompatible polymer, poly (lactic-co-glycolic acid). The sheets were then used as a drug diffusion barrier by capping and sealing a compressed tablet… (More)
DOI: 10.1016/j.jconrel.2010.10.023

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