A mutation of the circadian timing system (tau gene) in the seasonally breeding Syrian hamster alters the reproductive response to photoperiod change.

@article{Stirland1996AMO,
  title={A mutation of the circadian timing system (tau gene) in the seasonally breeding Syrian hamster alters the reproductive response to photoperiod change.},
  author={J Anne Stirland and Younas Mohammad and Andrew S. I. Loudon},
  journal={Proceedings. Biological sciences},
  year={1996},
  volume={263 1368},
  pages={345-50}
}
The tau mutation is a semi-dominant autosomal mutation which, in homozygotes, accelerates the period of the circadian activity cycle by approximately 4 h. In mammals, the circadian system contributes to seasonal photoperiodic time measurement by generating a repeated daily melatonin signal during the hours of darkness. Our earlier studies suggest an altered response to the melatonin signal in tau mutants. This study investigated whether tau and wild-type hamsters exhibit a differential response… CONTINUE READING

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