A mutation in the Neurospora crassa actin gene results in multiple defects in tip growth and branching.

@article{Virag2004AMI,
  title={A mutation in the Neurospora crassa actin gene results in multiple defects in tip growth and branching.},
  author={Aleksandra Virag and Anthony J. F. Griffiths},
  journal={Fungal genetics and biology : FG & B},
  year={2004},
  volume={41 2},
  pages={213-25}
}
Actin has a pivotal function in hyphal morphogenesis in filamentous fungi, but it is not certain whether its function is equivalent to that of a morphogen, or if it is simply part of a mechanism that executes orders given by another regulatory entity. To address this question we selected for cytochalasin A resistance and isolated act1, the first actin mutant in Neurospora crassa. This mutant branches apically and shows an altered distribution of actin at the tip. Based on the properties of this… CONTINUE READING