A mutation in Escherichia coli K-12 results in a requirement for thiamine and a decrease in L-serine deaminase activity.

Abstract

Mutants of Escherichia coli K-12 deficient in L-serine deaminase (L-SD) activity have been isolated. These strains required thiamine and grew normally when it was provided. The decrease in L-SD activity caused no obvious metabolic deficiency. A study of revertants and transductants showed that a single mutation was responsible for the thiamine requirement and for the decrease in L-SD activity.

Cite this paper

@article{Newman1985AMI, title={A mutation in Escherichia coli K-12 results in a requirement for thiamine and a decrease in L-serine deaminase activity.}, author={Elaine B. Newman and Bruce A. Miller and Leonard Colebrook and Charline Walker}, journal={Journal of bacteriology}, year={1985}, volume={161 1}, pages={272-6} }