A mutated swi4 gene causes duplications in the mating-type region of Schizosaccharomyces pombe

@article{Fleck2004AMS,
  title={A mutated swi4 gene causes duplications in the mating-type region of Schizosaccharomyces pombe},
  author={Oliver Fleck and Lutz Heim and Herbert Gutz},
  journal={Current Genetics},
  year={2004},
  volume={18},
  pages={501-509}
}
SummaryEfficient mating-type (MT) switching in homothallic strains of Schizosaccharomyces pombe is significantly reduced if they have a mutation in any of the eleven known swi genes. The swi4 mutation causes heterothallic as well as homothallic segregants, both of which have duplications in the MT region. In contrast to homothallic strains, h+swi4 strains yield only a few duplications. The duplications originate in the process of MT switching, presumably by mistakes in the resolution of DNA… 

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